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  2. Depression and immune function - Wikipedia

    en.wikipedia.org/wiki/Depression_and_immune_function

    One explanation for the connection between inflammation and depression symptoms, is that depression is a disorder that stems from immune responses across the body. [13] Due in large part to the systems that bring them about both involving the same pro-inflammatory cytokines, the suggestion is that strong or prolonged immune responses allow for ...

  3. Evolutionary approaches to depression - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_approaches_to...

    One reason depression is thought to be a pathology is that it causes so much psychic pain and distress. However, physical pain is also very distressful, yet it has an evolved function: to inform the organism that it is being damaged, to motivate it to withdraw from the source of damage, and to learn to avoid such damage-causing circumstances in the future.

  4. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...

  5. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    Sleep deprivation and light therapy both target the same brain neurotransmitter system and brain areas as antidepressant drugs, and are now used clinically to treat depression. [28] Light therapy, sleep deprivation and sleep time displacement (sleep phase advance therapy) are being used in combination quickly to interrupt a deep depression in ...

  6. Late life depression - Wikipedia

    en.wikipedia.org/wiki/Late_life_depression

    Risk factors for depression in older persons include a history of depression, social isolation, lower socioeconomic status, uncontrolled pain, co-morbid chronic medical illness, insomnia, female sex, being single or divorced, cognitive or functional impairment, brain disease, alcohol use disorder, use of certain medications, stressful life ...

  7. Pseudodementia - Wikipedia

    en.wikipedia.org/wiki/Pseudodementia

    In contrast to major depression, dementia is a progressive neurodegenerative syndrome involving a pervasive impairment of higher cortical functions resulting from widespread brain pathology. [ 7 ] A significant overlap in cognitive and neuropsychological dysfunction in dementia and pseudodementia patients increases the difficulty in diagnosis.

  8. Depressant - Wikipedia

    en.wikipedia.org/wiki/Depressant

    When depressants are used, effects often include ataxia, anxiolysis, pain relief, sedation or somnolence, cognitive or memory impairment, as well as, in some instances, euphoria, dissociation, muscle relaxation, lowered blood pressure or heart rate, respiratory depression, and anticonvulsant effects.

  9. Pain - Wikipedia

    en.wikipedia.org/wiki/Pain

    Most pain resolves once the noxious stimulus is removed and the body has healed, but it may persist despite removal of the stimulus and apparent healing of the body. Sometimes pain arises in the absence of any detectable stimulus, damage or disease. [3] Pain is the most common reason for physician consultation in most developed countries.

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