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In biochemistry, denaturation is a process in which proteins or nucleic acids lose folded structure present in their native state due to various factors, including application of some external stress or compound, such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), agitation and radiation, or heat. [3]
Aversive agents—primarily bitterants and pungent agents—are often used to produce an unpleasant flavor. For example, the bitterant denatonium might be added to food used in a laboratory, where such food is not intended for human consumption. [1] A poisonous substance may be added as an even more powerful deterrent.
Guanidinium thiocyanate can be used to deactivate a virus, such as the influenza virus that caused the 1918 "Spanish flu", so that it can be studied safely.. Guanidinium thiocyanate is also used to lyse cells and virus particles in RNA and DNA extractions, where its function, in addition to its lysing action, is to prevent activity of RNase enzymes and DNase enzymes by denaturing them.
1 US gallon or 3.785 litres of denatured alcohol in a metal container. Denatured alcohol, also known as methylated spirits, metho, or meths in Australia, Ireland, New Zealand, South Africa, and the United Kingdom, and as denatured rectified spirit, is ethanol that has additives to make it poisonous, bad-tasting, foul-smelling, or nauseating to discourage its recreational consumption.
The Houston Advanced Research Center, commonly referred to as HARC, is a 501(c)(3) not-for-profit organization based in The Woodlands, Texas with the aim of improving human and ecosystem well-being through the application of sustainability science and principles of sustainable development. HARC employs a staff of about 30 researchers and ...
Denaturing High Performance Liquid Chromatography (DHPLC) is a method of chromatography for the detection of base substitutions, small deletions or insertions in the DNA. [1] Due to its speed and high resolution, this method is particularly useful for finding polymorphisms in DNA.
Greater Houston, designated by the United States Office of Management and Budget as Houston–The Woodlands–Sugar Land, [4] [5] [6] is the fifth-most populous metropolitan statistical area in the United States, [7] [8] [9] encompassing nine counties along the Gulf Coast in Southeast Texas.
Houston, Harris County, with a population of 2,320,268 (greater metropolitan area over 7,000,000) is one of the largest metropolitan areas in the US with its central, downtown area located 75 miles (121 km) by air southwest of the town of Kountze, Hardin County.