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Tianeptine/naloxone (developmental code names TNX-601, TNX-601-CR, TNX-601-ER), or naloxone/tianeptine, is an extended-release combination of tianeptine, an atypical μ-opioid receptor agonist, and naloxone, an orally inactive μ-opioid receptor antagonist, which was under development for the treatment of major depressive disorder, post-traumatic stress disorder (PTSD), and neurocognitive ...
Armed conflicts and attacks. Israel–Hamas war. Israeli invasion of the Gaza Strip. 29 October 2024 Beit Lahia airstrike. At least 93 Palestinians are killed and 40 others are missing in Israeli strikes on a residential building in Beit Lahia in northern Gaza.
Tonix is currently developing an extended-release form of TNX-601 ER (tianeptine oxalate extended-release tablets), a naloxone-free formulation of TNX-601, to treat major depressive disorder. [80] In October 2022, Tonix announced that the U.S. Food and Drug Administration (FDA) cleared the Investigational New Drug (IND) application for TNX-601 ...
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August 21, 2023. On today’s episode of CNN 10, Hurricane Hilary slams into the West Coast. Then, a race for the lunar south pole. Coy Wire explains why scientists are so keen to explore its ...