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Mephentermine, sold under the brand name Wyamine among others, is a sympathomimetic medication which was previously used in the treatment of low blood pressure but is mostly no longer marketed. [ 6 ] [ 5 ] [ 4 ] [ 7 ] [ 8 ] It is used by injection into a vein or muscle , by inhalation , and by mouth .
Serious side effects may include kidney problems, liver problems, low blood pressure, and malignant hyperthermia. [5] [4] It is unclear if it is safe in either pregnancy or breastfeeding. [5] It is only recommended in those who have a normal level of consciousness and stable blood pressure and heart rate. [4] It is classified as a volatile ...
An inhaler (puffer, asthma pump or allergy spray) is a medical device used for delivering medicines into the lungs through the work of a person's breathing. This allows medicines to be delivered to and absorbed in the lungs, which provides the ability for targeted medical treatment to this specific region of the body, as well as a reduction in the side effects of oral medications.
Pulmonary drug delivery is a route of administration in which patients use an inhaler to inhale their medications and drugs are absorbed into the bloodstream via the lung mucous membrane. This technique is most commonly used in the treatment of lung diseases, for example, asthma and chronic obstructive pulmonary disease (COPD).
This inhaler, known as "Siegle's steam spray inhaler", used the Venturi principle to atomize liquid medication, and this was the very beginning of nebulizer therapy. The importance of droplet size was not yet understood, so the efficacy of this first device was unfortunately mediocre for many of the medical compounds.
This makes it easier to use the inhaler and helps ensure that more of the medication gets into the lungs instead of just into the mouth or the air. Proper use of a spacer can make an inhaler more effective in delivering medicine. [9] Spacers can be especially helpful to adults and children who find a regular metered dose inhaler hard to use.
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Static lung compliance is the change in volume for any given applied pressure. [1] Dynamic lung compliance is the compliance of the lung at any given time during actual movement of air. Low compliance indicates a stiff lung (one with high elastic recoil) and can be thought of as a thick balloon – this is the case often seen in fibrosis.