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In October, Scholar Rock’s Phase 3 SAPPHIRE trial of apitegromab for SMA achieved its primary endpoint, demonstrating a statistically significant and clinically meaningful improvement for ...
Sapphire I was a 12-week placebo-controlled, randomized, double-blind trial which had a primary endpoint of cure (SVR 12) rate in non-cirrhotic patients with HCV GT1a and GT1b - who were new to HCV treatment - and were given Viekira Pak and ribavirin (RBV). Sapphire I reported a 96% cure rate. [23]
Successful clinical-trial results recently made Scholar Rock one of the stock market's top performers.
Sitravatinib is being evaluated in ongoing trials in patients with advanced non-small cell lung cancer, including in a combination trial with nivolumab in those who are resistant to checkpoint inhibitor therapy, and certain patients who are naïve to checkpoint inhibitor therapy.
The firm was founded in 1996 as the venture capital arm of multinational software conglomerate SAP [26] and spun out as an independent company in 2011, rebranding to Sapphire Ventures in 2014. [27] At the time, Sapphire Ventures managed $1.4 billion and had invested in more than 125 companies, with 10 companies going public and 17 getting acquired.
The antibody treatment, sasanlimab, in combination with Bacillus Calmette-Guérin (BCG) vaccine met the main goal of the study in patients with high-risk non-muscle invasive bladder cancer (NMIBC ...
A star sapphire is a type of sapphire that exhibits a star-like phenomenon known as asterism; red stones are known as "star rubies". Star sapphires contain intersecting needle-like inclusions following the underlying crystal structure that causes the appearance of a six-rayed "star"-shaped pattern when viewed with a single overhead light source.
Similar to Pokémon Omega Ruby and Alpha Sapphire, a special demo was released on 18 October 2016. [18] On 27 October 2016 during Nintendo's Financial Briefing, they stated the demo had been downloaded more than 3.5 million times, being the most popular and fastest "selling" demo in 3DS history. [50]