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Mammals have multiple isoforms (at least 6 different gene products plus splice variants) of epithelial chloride channel proteins, catalogued into the Chloride channel accessory (CLCA) family. [8] The first member of this family to be characterized was a respiratory epithelium, Ca 2+ -regulated, chloride channel protein isolated from bovine ...
Chloride intracellular channel 4, also known as CLIC4,p644H1,HuH1, is a eukaryotic gene. [5]Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume.
Chloride intracellular channel protein 1 is a protein that in humans is encoded by the CLIC1 gene. [5] [6]Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume.
Chloride intracellular channel protein 2 is a protein that in humans is encoded by the CLIC2 gene. [3] [4]Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume.
Chloride channel protein, skeletal muscle (CLCN1) is a protein that in humans is encoded by the CLCN1 gene. [6] Mutations in this protein cause congenital myotonia. CLCN1 is critical for the normal function of skeletal muscle cells. For the body to move normally, skeletal muscles must tense (contract) and relax in a coordinated way.
Chloride channels: This superfamily of channels consists of approximately 13 members. They include ClCs, CLICs, Bestrophins and CFTRs. These channels are non-selective for small anions; however chloride is the most abundant anion, and hence they are known as chloride channels. Potassium channels. Voltage-gated potassium channels e.g., Kvs, Kirs ...
The Calcium-Dependent Chloride Channel (Ca-ClC) proteins (or calcium-activated chloride channels (CaCCs), [2] are heterogeneous groups of ligand-gated ion channels for chloride that have been identified in many epithelial and endothelial cell types as well as in smooth muscle cells.
Chloride intracellular channel protein 5 is a protein that in humans is encoded by the CLIC5 gene. [5] [6] Expression and localization. CLIC5 exists in two ...