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Reelin's name comes from the abnormal reeling gait of reeler mice, [17] which were later found to have a deficiency of this brain protein and were homozygous for mutation of the RELN gene. The primary phenotype associated with loss of reelin function is a failure of neuronal positioning throughout the developing central nervous system (CNS).
The Disabled-1 (Dab1) gene encodes a key regulator of Reelin signaling. Reelin is a large glycoprotein secreted by neurons of the developing brain, particularly Cajal-Retzius cells. DAB1 functions downstream of Reln in a signaling pathway that controls cell positioning in the developing brain and during adult neurogenesis.
Several programming languages and libraries provide functions for fast and vectorized clamping. In Python, the pandas library offers the Series.clip [1] and DataFrame.clip [2] methods. The NumPy library offers the clip [3] function. In the Wolfram Language, it is implemented as Clip [x, {minimum, maximum}]. [4]
Python is a high-level, general-purpose programming language. Its design philosophy emphasizes code readability with the use of significant indentation. [33] Python is dynamically type-checked and garbage-collected. It supports multiple programming paradigms, including structured (particularly procedural), object-oriented and functional ...
A snippet of Python code with keywords highlighted in bold yellow font. The syntax of the Python programming language is the set of rules that defines how a Python program will be written and interpreted (by both the runtime system and by human readers). The Python language has many similarities to Perl, C, and Java. However, there are some ...
When a function has to tail-call another, instead of calling it directly and then returning the result, it returns the address of the function to be called and the call parameters back to the trampoline (from which it was called itself), and the trampoline takes care of calling this function next with the specified parameters.
A built-in function, or builtin function, or intrinsic function, is a function for which the compiler generates code at compile time or provides in a way other than for other functions. [23] A built-in function does not need to be defined like other functions since it is built in to the programming language. [24]
A helper function is a function which groups parts of computation by assigning descriptive names and allowing for the reuse of the computations. [6] Although not all wrappers are helper functions, all helper functions are wrappers, and a notable use of helper functions—grouping frequently utilized operations—is in dynamic binary translation, in which helper functions of a particular ...