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Progestogen-only pills may also be prescribed for individuals wanting an oral form of birth control but do not wish to use estrogen-containing methods due to medical contraindications, intolerable side effects, or personal preference. [8]
At very low daily dose of 30 μg, levonorgestrel is used in some progestogen-only pill formulations. [23] Levonorgestrel is the active ingredient in a number of intrauterine devices including Mirena and Skyla. [23] [24] It is also the active ingredient in the birth control implants Norplant and Jadelle. [23] [24]
Birth control pills come in a variety of formulations. The main division is between combined oral contraceptive pills, containing both estrogens and synthetic progestogens , and progestogen only pills. Combined oral contraceptive pills also come in varying types, including varying doses of estrogen, and whether the dose of estrogen or ...
Chlormadinone acetate (CMA), sold under the brand names Belara, Gynorelle, Lutéran, and Prostal among others, is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy, as a component of menopausal hormone therapy, in the treatment of gynecological disorders, and in the treatment of androgen-dependent conditions like enlarged prostate and prostate ...
The risk of thromboembolism varies with different types of birth control pills; compared with combined oral contraceptives containing levonorgestrel (LNG), and with the same dose of estrogen and duration of use, the rate ratio of deep venous thrombosis for combined oral contraceptives with norethisterone is 0.98, with norgestimate 1.19, with ...
CPA/EE-containing birth control pills were developed by 1975 [20] [21] and were first introduced for medical use in 1978. [22] They originally contained 50 μg EE (Diane); subsequently, the EE dosage was decreased to 35 μg in a new "low-dose" preparation in 1986 (Diane-35).
The first birth control patch, "Ortho Evra" was first introduced in 2002. [51] In 2014, a generic version of Ortho Evra was released and called "Xulane". [ 52 ] In 2020, the FDA approved Twirla, a low-dose transdermal combined hormonal contraceptive.
[18] [19] [20] Today's standard dose oral contraceptives contain an estrogen dose that is one third lower than the first marketed oral contraceptive and contain lower doses of different, more potent progestins in a variety of formulations. [15] [17] [21] Enovid was discontinued in the U.S. in 1988, along with other first-generation high ...
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