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  2. Anti-histone antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-histone_antibodies

    Ninety-six percent of patients with lupus induced by procainamide will have a positive test for anti-histone antibodies, and 100% of patients whose lupus was induced by penicillamine, isoniazid, or methyldopa will have a positive test for anti-histone antibodies. In 70% of patients with rheumatoid arthritis, Felty's syndrome, Sjogren's syndrome ...

  3. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    ANA testing for lupus is highly sensitive, with the vast majority of individuals with Lupus testing positive; but the test is not specific, as a positive result may or may not be indicative of Lupus. [100] Several techniques are used to detect ANAs. The most widely used is indirect immunofluorescence (IF). The pattern of fluorescence suggests ...

  4. Lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Lupus_erythematosus

    Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs.

  5. Lupus anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Lupus_anticoagulant

    The "lupus anticoagulant paradox" [6] may be explained by platelet activation as described above, as well as enhancement of activated protein C resistance and suppression of the anticoagulant activity of TFPIα. Another proposed mechanism is the antibody-mediated destruction of Annexin A5 on the membranes of endothelial cells and trophoblast cells.

  6. The Root Cause Of Lupus Has Been A Complete Mystery ... - AOL

    www.aol.com/root-cause-lupus-complete-mystery...

    Lupus is a chronic disease that can cause inflammation and pain in any part of the body. The disease impacts about 1.5 million Americans, but women are nine times more likely to develop lupus than ...

  7. Anti-dsDNA antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-dsDNA_antibodies

    Increases in titres of the antibodies can coincide with, or even precede an increase of disease activity. For this reason titres are serially monitored by clinicians to assess disease progression. Titres are monitored more often in cases of more active lupus than that of less active lupus at intervals of 1–3 months and 6–12 months ...

  8. Lupus band test - Wikipedia

    en.wikipedia.org/wiki/Lupus_band_test

    The skin is from a person with systemic lupus erythematosus and shows IgG deposits at two different places: The first is a bandlike deposit along the epidermal basement membrane ("lupus band test" is positive); the second is within the nuclei of the epidermal cells (antinuclear antibodies are present).

  9. LE cell - Wikipedia

    en.wikipedia.org/wiki/LE_cell

    A lupus erythematosus cell (LE cell), also known as Hargraves cell, is a neutrophil or macrophage that has phagocytized (engulfed) the denatured nuclear material of another cell. [1] The denatured material is an absorbed hematoxylin body (also called an LE body).

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