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Other considerations include procedural considerations, the presence of inflammation, techniques used to administer the anesthetic medication, and adverse effects. [1] In root canal treatment, for example, more Lidocaine is required than for a simple filling. [2]
Severe side effects may include anaphylaxis, seizures, and Clostridioides difficile-associated diarrhea. [3] It is unclear if use during pregnancy is safe. [4] Meropenem works by blocking the construction of the bacterial cell wall while vaborbactam blocks the breakdown of meropenem by some beta-lactamases. [3]
Lidocaine is an antiarrhythmic medication of the class Ib type. [7] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [10] [7] When injected near nerves, the nerves cannot conduct signals to or from the brain. [8] Lidocaine was discovered in 1946 and went on sale in 1948. [11]
Carbapenems are contraindicated in patients with prior allergic reactions to beta lactam antibiotics. In addition, as the intramuscular formulations of ertapenem and imipenem are formulated with lidocaine, the intramuscular formulation of these two drugs are contraindicated in patients with prior adverse reactions to lidocaine.
Adverse effects depend on the local anesthetic method and site of administration discussed in depth in the local anesthetic sub-article, but overall, adverse effects can be: localized prolonged anesthesia or paresthesia due to infection, hematoma , excessive fluid pressure in a confined cavity, and severing of nerves & support tissue during ...
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
Potential adverse effects on cardiovascular activities are listed below: [44] Increase in myocardial oxygen demand due to a rise in heart rate, blood pressure and cardiac output Increase in pulmonary arterial pressure, which could be fatal in patients with ischemic heart disease , systemic or pulmonary hypertension
The GI cocktail is a mixture of a viscous anesthetic, an antacid, and an anticholinergic. [1] [2] Common viscous anesthetics use are viscous lidocaine or xylocaine.Common antacids used are magnesium hydroxide, aluminum hydroxide, or simethicone (more commonly known as Mylanta or Maalox). [3]
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