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Metoprolol, sold under the brand name Lopressor among others, is a medication used to treat angina and a number of conditions involving an abnormally fast heart rate. [4] It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines . [ 4 ]
The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...
The therapeutic ratio in radiotherapy for cancer treatment is determined by the maximum radiation dose for killing cancer cells and the minimum radiation dose causing acute or late morbidity in cells of normal tissues. [13] Both of these parameters have sigmoidal dose–response curves. Thus, a favorable outcome in dose–response for tumor ...
The study analyzed data from nearly 10,000 people who were enrolled in a randomized clinical trial, looking into the impact of low-dose aspirin on reducing heart disease risk in Australian and ...
The WHO's definition is: "The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults." [ 1 ] The Defined Daily Dose was first developed in the late 1970s.
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The dose for TB meningitis is dexamethasone 8 to 12 mg daily tapered off over six weeks (for those who prefer more precise dosing should refer to Thwaites et al., 2004 [34]). The dose for pericarditis is prednisolone 60 mg daily tapered off over four to eight weeks.
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