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Foot of an 80-year old individual with type 2 diabetes and heart failure. The second toe has a large ischaemic ulcer. The first toe has a small one. The prevalence of arterial insufficiency ulcers among people with Diabetes is high due to decreased blood flow caused by the thinning of arteries and the lack of sensation due to diabetic neuropathy.
Anti-ulcer agents are medications or supplements used to cure the damage of mucosal layer on organs to prevent the damage from further extending to deeper regions to cause complications. An anti-ulcer medication for treating mouth ulcer is triamcinolone, a corticosteroid. Other anti-ulcer supplements include vitamin B2 and vitamin B12.
Curcumin (turmeric) therapy, in conjunction with taking the medications mesalamine or sulfasalazine, may be effective and safe for maintaining remission in people with quiescent ulcerative colitis. [158] [159] The effect of curcumin therapy alone on quiescent ulcerative colitis is unknown. [159] Treatments using cannabis or cannabis oil are ...
Negative pressure wound therapy (NPWT) is a treatment that improves ischemic tissues and removes wound fluid used by bacteria. [ 8 ] [ 14 ] This therapy, also known as vacuum-assisted closure, reduces swelling in tissues, which brings more blood and nutrients to the area, as does the negative pressure itself. [ 8 ]
Critical limb ischemia is diagnosed by the presence of ischemic rest pain, and an ulcers that will not heal or gangrene due to insufficient blood flow. [3] Insufficient blood flow may be confirmed by ankle-brachial index (ABI), ankle pressure, toe-brachial index (TBI), toe systolic pressure, transcutaneous oxygen measurement (TcpO2 ), or skin perfusion pressure (SPP).
Martorell's ulcer, also known as hypertensive leg ulcer or necrotic angiodermatitis, [1] is a painful ulceration of the lower leg associated with diastolic [citation needed] arterial hypertension. It was first identified by the Spanish cardiologist Fernando Martorell in 1945, [ 3 ] [ 4 ] who referred to the ulcers as 'hypertensive ischaemic ...
Venous ulcers are costly to treat, and there is a significant chance that they will recur after healing; [3] [10] one study found that up to 48% of venous ulcers had recurred by the fifth year after healing. [10] However treatment with local anaesthetic endovenous techniques suggests a reduction of this high recurrence rate is possible. [48]
These drugs are often first-line treatment for the target diseases and are effective in tackling the symptoms. An example of the target disease is ischemic heart disease. Some examples of commonly prescribed drugs for this disease are beta-blockers, calcium-channel blockers and nitrates.