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HPV+OPC presents in one of four ways: as an asymptomatic abnormality in the mouth found by the patient or a health professional such as a dentist; with local symptoms such as pain or infection at the site of the tumor; with difficulties of speech, swallowing, and/or breathing; or as a swelling in the neck (if the cancer has spread to lymph nodes).
Human papillomavirus (HPV)-associated oropharyngeal cancer awareness and prevention is a vital concept from a public and community health perspective. HPV is the sexually transmitted virus that is known to be the cause of genital warts. There are currently more than 100 different strains of HPV, half of which can cause genital infections. [1]
Over 20 different high-risk HPV subtypes have been implicated in causing head and neck cancer. In particular, HPV-16 is responsible for up to 90% of oropharyngeal cancer in North America. [56] Approximately 15–25% of head and neck cancers contain genomic DNA from HPV, [66] and the association varies based on the site of the tumor. [67]
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Oropharyngeal cancer, [1] [2] [3] also known as oropharyngeal squamous cell carcinoma and tonsil cancer, [1] is a disease in which abnormal cells with the potential to both grow locally and spread to other parts of the body are found in the oral cavity, in the tissue of the part of the throat that includes the base of the tongue, the tonsils, the soft palate, and the walls of the pharynx.
Vaccinated men had a lower risk of developing any HPV-related cancer, such as cancers of the anus, penis and mouth and throat. These cancers take years to develop so the numbers were low: There were 57 HPV-related cancers among the unvaccinated men — mostly head and neck cancers — compared to 26 among the men who had the HPV vaccine.
More: Vaccine for HPV, the nation's most common sexually transmitted infection, proves effective. There are over 40 kinds of HPV that can impact the genital area, per Mayo Clinic. The strains of ...
Treatment for cervical cancer has gotten better over time, but the best strategy to avoid it is to get the HPV vaccine, which has been shown to reduce rates of cervical cancer, Blank explains.
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