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Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).
mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...
Some studies showed a low vaccination rate against some Vaccine-preventable disease among patients taking immunosuppressive drugs, despite a generally positive attitude towards vaccinations. [ 13 ] There are also other side-effects, such as hypertension , dyslipidemia , hyperglycemia , peptic ulcers , lipodystrophy , moon face , liver injury ...
Umirolimus (INN/USAN, also called Biolimus) is an immunosuppressant, a macrocyclic lactone, a highly lipophilic derivative of sirolimus.This drug is proprietary to Biosensors International, which uses it in its own drug-eluting stents, and licenses it to partners such as Terumo.
A temperature below 30 °C (86 °F) should be avoided, as adverse events increase significantly. [24] The person should be kept at the goal temperature plus or minus half a degree Celsius for 24 hours. [24] Rewarming should be done slowly with suggested speeds of 0.1 to 0.5 °C (0.18 to 0.90 °F) per hour. [24]
Sirolimus (also known as rapamycin) is an antifungal and immunosuppressant that has been isolated from S. hygroscopicus from soil samples from Easter Island. [4] Ascomycin is another immunosuppressant produced by some strains of S. hygroscopicus; it has a similar structure to sirolimus and can be used to treat autoimmune diseases and skin diseases and can help prevent rejection after an organ ...
Many CD40 Ligand Deficiency are first diagnosed after having PCP in their first year of life. The fungus is common and is present in over 70% of healthy people's lungs, however, Hyper IgM patients are not able to fight it off without the administration of Bactrim [medical citation needed] Hepatitis (Hepatitis C) Chronic diarrhea; Hypothyroidism ...
Basiliximab, sold under the brand name Simulect, is a monoclonal antibody used to prevent rejection in kidney transplants. [2] [3] It is a chimeric mouse-human monoclonal antibody to the α chain of the IL-2 receptor of T cells. [2] It is used in combination with other medicines used to prevent organ rejection. [2] [3]