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For example, if the primary tumor grade was 2 and the secondary tumor grade was 3 but some cells were found to be grade 4, the Gleason score would be 2+4=6. This is a slight change from the pre-2005 Gleason system where the second number was the secondary grade (i.e., the grade of the second-most common cell line pattern).
3. Another typical Gleason score might be 7 (3+ 4), where the primary pattern has a Gleason grade of 3 and the secondary pattern has a grade of 4. 4. Finally, the highest possible Gleason score is 10 (5 + 5), when the primary and secondary patterns both have the most disordered Gleason grades of 5.
[4] 5) Clarify “risk” based on Gleason scale. Add: "A Gleason score of 6 is considered low risk and 3+4=7 is intermediate risk. Both 4+3=7 and 8-10 are considered high risk." [5] 6) Make Gleason Grade consistent throughout. i.e., In the article, it mentions G score, cancer grade, histologic grade, etc. We suggest replacing those with ...
In uncertain cases, a diagnosis of malignancy can be excluded by immunohistochemical detection of basal cells (or confirmed by absence thereof), [4] such as using the PIN-4 cocktail of stains, which targets p63, CK-5, CK-14 and AMACR (latter also known as P504S).
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The test takes 45–90 minutes to administer depending on the age of the participant. The mean score for the WIAT-II is 100 with a standard deviation of 15, and the scores on the test may range from 40 to 160. 68% of participants in the UK standardisation sample obtained scores of 85-115 and 95% obtained scores of 70-130.
Round 1 took place in 2008–13 (main study in 2011 [4]), supplementary Round 2 in 2012–16, and Round 3 in 2014–18 (main study in 2016–17). [7] Subsequent cycles will allow future changes in adult skills to be monitored and analysed and will provide first indications of where improvements have been achieved and deficits persist.
DIBELS (Dynamic Indicators of Basic Early Literacy Skills) is a series of short tests designed to evaluate key literacy skills among students in kindergarten through 8th grade, such as phonemic awareness, alphabetic principle, accuracy, fluency, and comprehension.