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  2. Haloperidol - Wikipedia

    en.wikipedia.org/wiki/Haloperidol

    Haloperidol, sold under the brand name Haldol among others, is a typical antipsychotic medication. [9] Haloperidol is used in the treatment of schizophrenia , tics in Tourette syndrome , mania in bipolar disorder , delirium , agitation, acute psychosis , and hallucinations from alcohol withdrawal .

  3. Haloperidol decanoate - Wikipedia

    en.wikipedia.org/wiki/Haloperidol_decanoate

    Haloperidol decanoate is provided in the form of 50 or 100 mg/mL oil solution of sesame oil and benzyl alcohol in ampoules or pre-filled syringes. [6] [7] [9] Its elimination half-life after multiple doses is 21 days. [10] [11] The medication is marketed in many countries throughout the world. [3] [12

  4. Antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Antipsychotic

    5 Mechanism of action. 6 Comparison of medications. 7 History. 8 Society and culture. ... Haloperidol decanoate: Haldol Decanoate: Typical: Sesame oil: 20–400 mg/2 ...

  5. Typical antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Typical_antipsychotic

    The first LAI antipsychotics (often referred to as simply "LAIs") were the typical antipsychotics fluphenazine and haloperidol. [18] Both fluphenazile and haloperidol are formulated as decanoates, referring to the attachment of a decanoic acid group to the antipsychotic molecule. [18] These are then dissolved in an organic oil. [18]

  6. Pharmacology of ethanol - Wikipedia

    en.wikipedia.org/wiki/Pharmacology_of_ethanol

    Thus, there remains lingering doubt about the mechanisms of ethanol listed here, even for the GABA A receptor, the most-studied mechanism. [24] In the past, alcohol was believed to be a non-specific pharmacological agent affecting many neurotransmitter systems in the brain, [25] but progress has been made over the last few decades.

  7. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    The mechanism of alcohol-related psychosis is due to distortions to neuronal membranes, gene expression, as well as thiamine deficiency. It is possible in some cases that alcohol abuse via a kindling mechanism can cause the development of a chronic substance-induced psychotic disorder (e.g., schizophrenia).

  8. List of investigational hallucinogens and entactogens - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    DLX-159 – undisclosed mechanism of action, serotonin 5-HT 2B receptor antagonist, and psychoplastogen – major depressive disorder, psychiatric disorders – Delix Therapeutics [98] [99] [100] EB-002 (EB-373; psilocin prodrug) – non-selective serotonin receptor agonist and psychedelic hallucinogen – anxiety disorders – Enveric ...

  9. Molecular and epigenetic mechanisms of alcoholism - Wikipedia

    en.wikipedia.org/wiki/Molecular_and_Epigenetic...

    The reason this mechanism is not used for acute tolerance is because tolerance depends on the modified protein synthesis, which takes time. The effect histone acetylation on BK channel expression and alcohol tolerance has been studied by Ghezzi et al. (2014) using the Drosophila. The Drosophila gene that encodes BK channels is called slowpoke (slo

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