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Most desmoid tumors arise in the extremities, such as your arms and legs, but sometimes they develop in the abdomen, too. So, the symptoms depend on the tumor’s size and location. For tumors in the extremities, patients usually notice a mass somewhere, growing at a very slow pace. For tumors in the abdomen, symptoms can range from mild pain ...
Importance Desmoid tumor (DT) is a rare and locally aggressive monoclonal, fibroblastic proliferation characterized by a variable and often unpredictable clinical course. Previously, surgery was the standard primary treatment modality; however, within the past decade, a paradigm shift toward less-invasive management has been introduced and an effort to harmonize the strategy among clinicians ...
Desmoid tumors (also called aggressive fibromatosis, deep musculoaponeurotic fibromatosis, and fibrosarcoma grade I of the desmoid type) are locally aggressive tumors with no known potential for metastasis or dedifferentiation. However, tumor invasion into vital structures and/or organs can result in substantial morbidity and may be fatal ...
Abdominal wall tumors are rare and include heterogeneous diseases. Among them, desmoid tumors are the most frequent and are often diagnosed in young women during or early after pregnancy; inflammatory response after trauma or microtrauma, such as after cesarean section, may favor their growth. A 37-year-old woman presented with a progressive mass in the abdominal wall after a cesarean section.
Salas S, Brulard C, Terrier P, et al. Gene Expression Profiling of Desmoid Tumors by cDNA Microarrays and Correlation with Progression-Free Survival. Clin Cancer Res 2015; 21:4194–4200 [Google Scholar] 19. Dufresne A, Paturel M, Alberti L, et al. Prediction of desmoid tumor progression using miRNA expression profiling.
Desmoid tumor symptoms differ based on where the tumors occur. Desmoid tumors most often happen in the abdomen, arms and legs. But they can form anywhere in the body. In general, signs and symptoms include: A mass or area of swelling. Pain. Loss of function in the affected area. Cramping and nausea, when desmoid tumors occur in the abdomen.
Tests and procedures used to diagnose desmoid tumors include: Physical exam. Your doctor will examine your body to better understand your signs and symptoms. Imaging tests. Your doctor may recommend imaging tests, such as CT and MRI, to create pictures of the area where your symptoms are occurring. The images may give your doctor clues about ...