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Allopurinol is a medication used to decrease high blood uric acid levels. [5] It is specifically used to prevent gout , prevent specific types of kidney stones and for the high uric acid levels that can occur with chemotherapy .
ATC code M04 Antigout preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. [1] [2] [3] Subgroup M04 is part of the anatomical group M Musculo-skeletal system. [4]
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According to the American College of Rheumatology guidelines, allopurinol is the first-line medication for lowering uric acid levels. Febuxostat is another uric acid-lowering medication that may ...
Probenecid can be used in a combined therapy with allopurinol is more effective than allopurinol monotherapy. [76] [77] [78] Pegloticase is an option for the 3% of people who are intolerant to other medications. [79] It is a third line agent. [64] Pegloticase is given as an intravenous infusion every two weeks, [79] and reduces uric acid levels ...
Drugs with other primary uses, that have known uricosuric properties, include losartan, [1] atorvastatin, and fenofibrate.Although these drugs may have significant uricosuric action, their other significant pharmacological actions in off-label use as a uricosuric requires careful assessment of the patient to achieve the most benefit and least risk.
A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism.In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. [1]
Lesinurad/allopurinol (trade name Duzallo) is a fixed-dose combination drug for the treatment of gout. [1] It contains 200 mg of lesinurad and 300 mg of allopurinol.In August 2017, the US Food and Drug Administration approved it for the treatment of hyperuricemia associated with gout in patients for whom target serum uric acid levels have not been achieved with allopurinol alone. [2]
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related to: antigout allopurinol- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
GoodRx was honored as dot.LA’s Startup of the Year for 2020. - dot.LA