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Articular cartilage, most notably that which is found in the knee joint, is generally characterized by very low friction, high wear resistance, and poor regenerative qualities. It is responsible for much of the compressive resistance and load bearing qualities of the knee joint and, without it, walking is painful to impossible.
Though articular cartilage damage is not life-threatening, it does strongly affect one's quality of life. Articular cartilage damage is often the cause of severe pain, knee swelling, substantial reduction in mobility and severe restrictions to one's activities. Over the last decades, however, research has focused on regenerating damaged joints.
Osteoarthritis: The cartilage covering bones (articular cartilage) is thinned, eventually completely worn out, resulting in a "bone against bone" joint, resulting in pain and reduced mobility. Osteoarthritis is very common, affects the joints exposed to high stress and is therefore considered the result of "wear and tear" rather than a true ...
In the knee joints, they observed an increased cartilage degeneration in the menopausal group. The group also had worse synovitis , which is inflammation of the synovium, a critical component of ...
ACI articular cartilage repair procedures take place in three stages. First, cartilage cells are extracted arthroscopically from the patient's healthy articular cartilage that is located in a non load-bearing area of either the intercondylar notch or the superior ridge of the femoral condyles.
The knee may become affected by almost any form of arthritis. [2] The word arthritis refers to inflammation of the joints. [3] [4] Types of arthritis include those related to wear and tear of cartilage, such as osteoarthritis, to those associated with inflammation resulting from an overactive immune system (such as rheumatoid arthritis). [5] [6]
Knee pain can be debilitating, making simple tasks like walking, climbing stairs, or even standing up a painful experience. For many, the quick fix seems to be a cortisone shot - an anti ...
A knee X-ray and/or blood test – this can assist to exclude certain types of arthritis or inflammation. Magnetic Resonance Imaging – to observe cartilage condition and assess deterioration; Arthroscopy – a low invasive approach to image the inside of the knee joint by inserting an endoscope into the knee joint. [16]
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