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[10] [47] Follow-up studies show that ongoing use of antidepressants leads to continuing improvement in depression over time; and also have demonstrated that moclobemide retains its therapeutic efficacy as an antidepressant for at least a year. This long-term efficacy is equivalent to that seen with other antidepressant classes.
Five of these trials showed no significant influence of vilazodone over placebo on depressive symptoms. [13] In the remaining two trials, small but significant advantages of vilazodone over placebo were found. [13] According to these two eight-week trials in adults, vilazodone has an antidepressant response after one week of treatment. [14]
Antidepressant exposure is not associated with an increased risk of spontaneous abortion. [55] There is a tentative association of SSRI use during pregnancy with heart problems in the baby. [56] The advantages of their use during pregnancy may thus not outweigh the possible negative effects on the baby. [56]
Mirtazapine, sold under the brand name Remeron among others, is an atypical tetracyclic antidepressant, and as such is used primarily to treat depression. [11] [12] Its effects may take up to four weeks but can also manifest as early as one to two weeks.
Over the years, several studies and meta-analyses have found that people who use bupropion to treat depression tend to gain less weight than their peers, with some people prescribed this ...
In the United States all antidepressants, including duloxetine carry a black box warning stating that antidepressants may increase the risk of suicide in persons younger than 25. This warning is based on statistical analyses conducted by two independent groups of FDA experts that found a 2-fold increase in the risk of suicidal ideation and ...
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