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In December 2003, a kidney stone weighing 356 g (12.5 oz) was removed from the right kidney of Peter Baulman of Australia. At its widest point, the stone measured 11.86 cm (4.66 in). [ 9 ] In 2017, a 2 kg (4.4 lb) stone spanning 20 cm was surgically removed from Abdul Abu Al Hajjar in Kensington , England.
Kidney stones are primarily composed of calcium salts, with the most common being calcium oxalate (70-80%), followed by calcium phosphate and uric acid. When urine contains high concentrations of these ions, they can form crystals and eventually stones. [41] The formation of kidney stones occurs in three main phases: [41]
Cystinuria is a cause of recurrent kidney stones. It is a disease involving the defective transepithelial transport of cystine and dibasic amino acids in the kidney and intestine, and is one of many causes of kidney stones.
The objective of treating IH is preventing nephrolithiasis or the formation of kidney stones. If blood calcium levels are normal, which can rule out hyperparathyroidism , treatment would begin with adopting a diet of ~800 mg of daily calcium, low salt intake, restricted animal protein intake, and increased net fluid intake. [ 8 ]
A single kidney stone in children or recurrent stones in adults is often the first warning sign of primary hyperoxaluria. Other symptoms range from recurrent urinary tract infections , severe abdominal pain or pain in the side, blood in the urine , to chronic kidney disease and kidney failure . [ 1 ]
In the general population, the frequency of medullary sponge kidney disease is reported to be 0.02–0.005%; that is, 1 in 5000 to 1 in 20,000. The frequency of medullary sponge kidney has been reported by various authors to be 12–21% in patients with kidney stones. [10] The disease is bilateral in 70% of cases. [citation needed]
[16] [17] [18] All stones are detectable on CT scans except very rare stones composed of certain drug residues in the urine. [19] In patients with recurrent ascending urinary tract infections, it may be necessary to exclude an anatomical abnormality, such as vesicoureteral reflux or polycystic kidney disease.
The signs and symptoms of hydronephrosis depend upon whether the obstruction is acute or chronic, partial or complete, unilateral or bilateral.Hydronephrosis that occurs acutely with sudden onset (as caused by a kidney stone) can cause intense pain in the flank area (between the hips and ribs) known as a renal colic.
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