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Glomerulonephritis (GN) is a term used to refer to several kidney diseases (usually affecting both kidneys). Many of the diseases are characterised by inflammation either of the glomeruli or of the small blood vessels in the kidneys, hence the name, [ 1 ] but not all diseases necessarily have an inflammatory component.
Acute proliferative glomerulonephritis is a disorder of the small blood vessels of the kidney.It is a common complication of bacterial infections, typically skin infection by Streptococcus bacteria types 12, 4 and 1 but also after streptococcal pharyngitis, for which it is also known as postinfectious glomerulonephritis (PIGN) or poststreptococcal glomerulonephritis (PSGN). [4]
Diffuse proliferative glomerulonephritis (DPGN) is a type of glomerulonephritis that is the most serious form of renal lesions in SLE and is also the most common, occurring in 35% to 60% of patients. [1] In absence of SLE, DPGN pathology looks more like Membranoproliferative glomerulonephritis [citation needed]
Glomerulonephrosis is a non-inflammatory disease of the kidney presenting primarily in the glomerulus (a glomerulopathy) as nephrotic syndrome.The nephron is the functional unit of the kidney and it contains the glomerulus, which acts as a filter for blood to retain proteins and blood lipids.
Renin–angiotensin system. Nephritis can produce glomerular injury, by disturbing the glomerular structure with inflammatory cell proliferation. [10] This can lead to reduced glomerular blood flow, leading to reduced urine output [11] and retention of waste products (). [12]
A diagram of the pathology of acute (poststreptoccal) glomerulonephritis that shows the immune complex deposits below the podocyte foot processes. This creates subepithelial humps. Date: 21 February 2010, 19:07 (UTC) Source: Renal_corpuscle.svg; Author: Renal_corpuscle.svg: M•Komorniczak-talk-(polish Wikipedist) derivative work: Huckfinne (talk)
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