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Meibomian glands in the lower eyelid imaged under amber light to show vasculature support and the gland structure. Meibomian gland dysfunction (MGD, also meibomitis or meibomianitis) is a chronic disease of the meibomian glands, which is commonly characterized by obstruction of the end of the duct that delivers the secretion produced by the glands (called meibum) to the eye surface, which ...
The most common cause of dry eye is increased evaporation of the tear film, typically as a result of meibomian gland dysfunction (MGD). The meibomian glands are two sets of oil glands that line the upper and lower eyelids and secrete the oily outer layer of the tear film—the lipid layer. These glands often become clogged due to inflammation ...
Meibomian gland dysfunction is more often seen in women and is regarded as the main cause of dry eye disease. [14] [15] Factors that contribute to meibomian gland dysfunction can include things such as a person's age and/or hormones, [16] or severe infestation of Demodex brevis mite.
Posterior blepharitis is an inflammation of the eyelids, secondary to dysfunction of the meibomian glands. Like anterior blepharitis, it is a bilateral chronic condition and may be associated with skin rosacea. [1] There is growing evidence that, in some cases, it is caused by demodex mites. [16]
The blocked gland is usually the meibomian gland, but can also be the gland of Zeis. [8] A stye and cellulitis may appear similar. [2] A stye, however, is usually more sudden in onset, painful, and occurs at the edge of the eyelid. [2] Cellulitis is also typically painful. [2] Treatment is initiated with warm compresses. [2]
Dry eyes are very common during treatment and is caused by isotretinoin's apoptotic effect on the meibomian glands. Some people develop contact lens intolerance as a result. [51] In some people, these changes are long-lasting or irreversible and represent Meibomian Gland Dysfunction (MGD). [44]
The periocular region, which includes the meibomian, Zeis, and sebaceous glands of the caruncle and eyelid, is the most common site accounting for up to 75% of SGc. [6] Meibomian glands are a type of sebaceous gland that lines the upper and lower eyelids and do not contain a follicle. The glands of Zeis contain the individual eyelash.
Moll's gland, also known as the gland of Moll or ciliary gland, is a modified apocrine sweat gland that is found on the margin of the eyelid. They are next to the base of the eyelashes, and anterior to the meibomian glands within the distal eyelid margin. These glands are relatively large and tubular-shaped.