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Korsakoff syndrome (KS) [1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation.This neurological disorder is caused by a deficiency of thiamine (vitamin B 1) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol. [2]
In some cases, the memory loss can extend back decades, while in other cases, people may lose only a few months of memory. Anterograde amnesia is the inability to transfer new information from the short-term store into the long-term store. People with anterograde amnesia cannot remember things for long periods of time.
The difference in memory between normal aging and a memory disorder is the amount of beta-amyloid deposits, hippocampal neurofibrillary tangles, or amyloid plaques in the cortex. If there is an increased amount, memory connections become blocked, memory functions decrease much more than what is normal for that age and a memory disorder is ...
Damage to the limbic system involves loss or damage to memory, and may include: [citation needed] loss or confusion of long-term memory prior to focal neuropathy (retrograde amnesia) inability to form new memories (anterograde amnesia) loss of, or reduced emotions ; loss of olfactory functions; loss of decision-making ability
Vascular thalamic amnesia occurs when the thalamus is affected by Korsakoff's syndrome or damaged by lacunar infarcts or hemorrhages. [1] Another common cause for damage to the thalamus that may contribute to the development of amnesia is a stroke. [ 2 ]
A person experiencing TGA has memory impairment; with an inability to remember events or people from the past few minutes, hours or days (retrograde amnesia) and has working memory of only the past few minutes or less, thus they cannot retain new information or form new memories beyond that period of time (anterograde amnesia). [4]
This is why after a stroke people have a chance of developing cognitive deficits that result in anterograde amnesia, since strokes can involve the temporal lobe in the temporal cortex, and the temporal cortex houses the hippocampus. Anterograde amnesia can be the first clinical sign that Alzheimer's disease is developing within the brain ...
Lacunar amnesia is the loss of memory about a specific event. This specific form of amnesia is caused by brain damage in the limbic system which is responsible for our memories and emotions. When the damage occurs it leaves a lacuna, or a gap, in the record of memory within the cortex region of the brain. There is a general belief that certain ...