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Mesotrione is a selective herbicide used mainly in maize crops. [1] It is a synthetic compound inspired by the natural substance leptospermone found in the bottlebrush tree Callistemon citrinus . It inhibits the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD) [ 3 ] and is sold under brand names including Callisto and Tenacity.
SC-0051 (sulcotrione) was synthesized and tested in Sept. – Oct. 1983, and SC-1296 (mesotrione) and SC-0735 (nitisinone) were both synthesized and tested in early 1984. Triketones were in widespread university field trials in 1985. [32] The first of the triketone patents was published in 1986. [33]
In the mid-1980s, scientists at Stauffer Chemical Company published patents to benzoyl-substituted cyclohexanediones which led to their product mesotrione. [3] This encouraged workers at Rhône-Poulenc to expand their own research into molecules with the same mode of action as these 4-hydroxyphenylpyruvate dioxygenase inhibitors .
Leptospermone is a chemical compound (a β-triketone) produced by some members of the myrtle family (), such as Callistemon citrinus (Lemon Bottlebrush), a shrub native to Australia, and Leptospermum scoparium (Manuka), a New Zealand tree from which it gets its name. [1]
eBay Inc. v. MercExchange, L.L.C., 547 U.S. 388 (2006), is a case in which the Supreme Court of the United States unanimously determined that an injunction should not be automatically issued based on a finding of patent infringement, but also that an injunction should not be denied simply on the basis that the plaintiff does not practice the patented invention. [1]
Methyl dihydrojasmonate (often referred to by its trade names of hedione or kharismal) is an aroma compound with an odour similar to that of jasmine.In racemic mixtures the odor is floral and citrus, while epimerized mixtures exhibit a dense buttery-floral odor with odor recognition thresholds of 15 parts per billion. [1]
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