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Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for head lice . [ 2 ] It is also in flea and tick killing products for pets.
Myristic acid (IUPAC name: tetradecanoic acid) is a common saturated fatty acid with the molecular formula CH 3 (CH 2) 12 COOH.Its salts and esters are commonly referred to as myristates or tetradecanoates.
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In 1982, Koiti Titani's lab identified an "N-terminal blocking group" on the catalytic subunit of cyclic AMP-dependent protein kinase in cows as n-tetradecanoyl. [6]Almost simultaneously in Claude B. Klee's lab, this same N-terminal blocking group was further characterized as myristic acid. [7]
Isoflurophate, the diisopropyl ester of fluorophosphoric acid, is made by reacting isopropyl alcohol with phosphorus trichloride, forming diisopropylphosphite, which is chlorinated and further reacted with sodium fluoride to replace the chlorine atom with fluorine, thus giving diisopropyl fluorophosphate. [8]
Isopropylamine can be obtained by reaction of isopropyl alcohol with ammonia in presence of a catalyst: [3] (CH 3) 2 CHOH + NH 3 → (CH 3) 2 CHNH 2 + H 2 O. Isopropylamine is a building block for the preparation of many herbicides and pesticides including atrazine, bentazon, glyphosate, imazapyr, ametryne, desmetryn, prometryn, pramitol, dipropetryn, propazine, fenamiphos, and iprodione. [3]
Isopropyl palmitate is the ester of isopropyl alcohol and palmitic acid. [2] It is an emollient , moisturizer , thickening agent , and anti-static agent . [ 3 ] The chemical formula is CH 3 (CH 2 ) 14 COOCH(CH 3 ) 2 .
DIPEA is a sterically hindered organic base that is commonly employed as a proton scavenger. Thus, like 2,2,6,6-tetramethylpiperidine and triethylamine, DIPEA is a good base but a poor nucleophile, DIPEA has low solubility in water, which makes it very easily recovered in commercial processes, a combination of properties that makes it a useful organic reagent.