Search results
Results from the WOW.Com Content Network
Unlike birds and fish, humans and other mammals are generally incapable of regrowing the cells of the inner ear that convert sound into neural signals when those cells are damaged by age or disease. [ 6 ] [ 24 ] Researchers are making progress in gene therapy and stem-cell therapy that may allow the damaged cells to be regenerated.
The hair cells are the primary auditory receptor cells and they are also known as auditory sensory cells, acoustic hair cells, auditory cells or cells of Corti. The organ of Corti is lined with a single row of inner hair cells and three rows of outer hair cells. The hair cells have a hair bundle at the apical surface of the cell.
The inner ear houses the apparatus necessary to change the vibrations transmitted from the outside world via the middle ear into signals passed along the vestibulocochlear nerve to the brain. The hollow channels of the inner ear are filled with liquid, and contain a sensory epithelium that is studded with hair cells. The microscopic "hairs" of ...
The study of hair cell regeneration mechanisms in adult zebrafish may be transferable to inducing hair cell regeneration in mammals. The basic structure and function of the fish's inner ear is similar to that of other vertebrates. Mammals share homologous genes with zebrafish that are known to affect inner ear structure and function. [17]
The organ of Corti is located in the scala media of the cochlea of the inner ear between the vestibular duct and the tympanic duct and is composed of mechanosensory cells, known as hair cells. [2] Strategically positioned on the basilar membrane of the organ of Corti are three rows of outer hair cells (OHCs) and one row of inner hair cells ...
Lightly resting atop the longest cilia of the inner hair cells is the tectorial membrane, which moves back and forth with each cycle of sound, tilting the cilia, which is what elicits the hair cells' electrical responses. Inner hair cells, like the photoreceptor cells of the eye, show a graded response, instead of the spikes typical of other ...
Humans have two otolithic organs on each side, one called the utricle, the other called the saccule. The utricle contains a patch of hair cells and supporting cells called a macula. Similarly, the saccule contains a patch of hair cells and a macula. Each hair cell of a macula has forty to seventy stereocilia and one true cilium called a ...
Type I spiral ganglion cells comprise the vast majority of spiral ganglion cells (90–95% in cats and 88% in humans [2]), and exclusively innervate the inner hair cells. They are myelinated, bipolar neurons. Type II spiral ganglion cells make up the remainder. In contrast to Type I cells, they are unipolar and unmyelinated in most mammals.