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Nephronophthisis is a genetic disorder of the kidneys which affects children. [3] It is classified as a medullary cystic kidney disease.The disorder is inherited in an autosomal recessive fashion and, although rare, is the most common genetic cause of childhood kidney failure.
Air trapping is common and leads to increased residual volumes. As the disease progresses, a mixed pattern of obstruction and restriction may develop. In general the obstructive lung disease is slowly progressive with periods of stability. [8]
[1] [2] [3] Causes of secondary NPH include trauma, hemorrhage, or infection. [4] The disease presents in a classic triad of symptoms, which are memory impairment, urinary frequency, and balance problems/gait deviations (note: this diagnosis method is obsolete [5] [6]). The disease was first described by Salomón Hakim and Raymond Adams in 1965 ...
Cerebral atrophy is a common feature of many of the diseases that affect the brain. [1] Atrophy of any tissue means a decrement in the size of the cell, which can be due to progressive loss of cytoplasmic proteins.
The onset of symptoms tends to be fairly gradual and to occur over 1-12 years. [citation needed] Symptoms of Hashimoto's encephalopathy may include: [citation needed] Personality changes; Aggression; Delusional behavior; Concentration and memory problems; Coma; Disorientation; Headaches; Jerks in the muscles (myoclonus – 65% of cases)
However, without treatment, permanent disability or death may occur. [1] Hydrocephalus affects about 0.1-0.6% of newborns. [4] Rates in the developing world may be higher. [5] Normal pressure hydrocephalus affects about 6% of patients over 80. [4] Description of hydrocephalus by Hippocrates dates back more than 2,000 years. [5]
Corticobasal degeneration (CBD) is a rare neurodegenerative disease involving the cerebral cortex and the basal ganglia. [1] CBD symptoms typically begin in people from 50 to 70 years of age, and typical survival before death is eight years.
The failure to breastfeed and amenorrhea no more periods, were seen as the syndrome (a collection of symptoms), but we now view Sheehan's as the pituitary failing to secrete 1-5 of the 9 hormones that it normally produces (the anterior (front) lobe of the pituitary produces FSH, LH, prolactin, ACTH (Adreno-cortico-trophic hormone),TSH (Thyroid ...