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2. DU145 - Wikipedia

   en.wikipedia.org/wiki/DU145

   DU145, PC3, and LNCaP are considered to be the standard prostate cancer cell lines used in therapeutic research. [ 1 ] The DU145 cell line was derived from a central nervous system metastasis , of primary prostate adenocarcinoma origin, removed during a parieto-occipital craniotomy of a 69-year-old, White, male.

3. Prostate cancer - Wikipedia

   en.wikipedia.org/wiki/Prostate_cancer

   Eventually cancer cells can grow resistant to this treatment. This most-advanced stage of the disease, called castration-resistant prostate cancer, is treated with continued hormone therapy alongside the chemotherapy drug docetaxel. Some tumors metastasize (spread) to other areas of the body, particularly the bones and lymph nodes.

4. PC3 - Wikipedia

   en.wikipedia.org/wiki/PC3

   PC3 cells have been utilized to research aggressive and castration-resistant forms of pancreatic cancer. The androgen-independence of these cells during cell division makes them invaluable for studying the molecular mechanisms embedded in studying advanced prostate cancer. [13] PC3 cells have been involved in research regarding the prevention ...

5. Lutetium (177Lu) vipivotide tetraxetan - Wikipedia

   en.wikipedia.org/wiki/Lutetium_(177Lu)_vipivot...

   Lutetium (177 Lu) vipivotide tetraxetan, sold under the brand name Pluvicto, is a radiopharmaceutical medication used for the treatment of prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer (mCRPC). [5] [6] Lutetium (177 Lu) vipivotide tetraxetan is a targeted radioligand therapy. [6] [8]

6. Opevesostat - Wikipedia

   en.wikipedia.org/wiki/Opevesostat

   Opevesostat is an investigational new drug being developed for the treatment of metastatic castration-resistant prostate cancer (mCRPC). [1] It is a non-steroidal, selective inhibitor of CYP11A1 (cholesterol side-chain cleavage enzyme) [2] discovered by Orion Corporation and currently undergoing clinical development by Merck & Co., Inc. Opevesostat's mechanism of action involves suppressing ...

7. Enzalutamide - Wikipedia

   en.wikipedia.org/wiki/Enzalutamide

   Enzalutamide, sold under the brand name Xtandi, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer. [2] [9] It is indicated for use in conjunction with castration in the treatment of metastatic castration-resistant prostate cancer (mCRPC), [2] nonmetastatic castration-resistant prostate cancer, [2] and metastatic castration-sensitive prostate ...

8. Sipuleucel-T - Wikipedia

   en.wikipedia.org/wiki/Sipuleucel-T

   Sipuleucel-T is indicated for the treatment of metastatic, asymptomatic or minimally symptomatic, metastatic castrate-resistant hormone-refractory prostate cancer (HRPC). Other names for this stage are metastatic castrate-resistant (mCRPC) and androgen independent (AI) or (AIPC). This stage leads to mCRPC with lymph node involvement and distal ...

9. Androgen deprivation therapy - Wikipedia

   en.wikipedia.org/wiki/Androgen_deprivation_therapy

   Lowering androgen levels or stopping them from getting into prostate cancer cells often makes prostate cancer shrink or grow more slowly for a time. However, this treatment needs to be combined with radiation therapy (RT) [8] because ADT itself does not eradicate the cancer; it just decreases its aggressiveness. [9]