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  2. Rolling hairpin replication - Wikipedia

    en.wikipedia.org/wiki/Rolling_hairpin_replication

    1. The coding portion of the genome is replicated, starting from the 3′-end of the 3′ hairpin, which acts as a primer, and continues until the newly synthesized strand is connected to the 5′-end of the 5′ hairpin, producing a duplex DNA molecule that has two strands of the coding portion of the genome.

  3. Directionality (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Directionality_(molecular...

    A furanose (sugar-ring) molecule with carbon atoms labeled using standard notation. The 5′ is upstream; the 3′ is downstream. DNA and RNA are synthesized in the 5′-to-3′ direction. Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of nucleic acid.

  4. Parvoviridae - Wikipedia

    en.wikipedia.org/wiki/Parvoviridae

    Replication begins once NS1 binds to and makes a nick in a replication origin site in the duplex DNA molecule at the end of one hairpin. Nicking releases the 3′-end of the nicked strand as a free hydroxyl (-OH) to prime DNA synthesis [2] with NS1 remaining attached to the 5′-end. [7]

  5. Three prime untranslated region - Wikipedia

    en.wikipedia.org/wiki/Three_prime_untranslated...

    In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. The 3′-UTR often contains regulatory regions that post-transcriptionally influence gene expression .

  6. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    DNA strands have a directionality, and the different ends of a single strand are called the "3′ (three-prime) end" and the "5′ (five-prime) end". By convention, if the base sequence of a single strand of DNA is given, the left end of the sequence is the 5′ end, while the right end of the sequence is the 3end.

  7. Sticky and blunt ends - Wikipedia

    en.wikipedia.org/wiki/Sticky_and_blunt_ends

    When a molecule of DNA is double stranded, as DNA usually is, the two strands run in opposite directions. Therefore, one end of the molecule will have the 3' end of strand 1 and the 5' end of strand 2, and vice versa in the other end. [2] However, the fact that the molecule is two stranded allows numerous different variations.

  8. Negative-strand RNA virus - Wikipedia

    en.wikipedia.org/wiki/Negative-strand_RNA_virus

    Excluding viruses in the genus Tenuivirus and some in the family Chuviridae, all −ssRNA viruses have linear rather than circular genomes, and the genomes may be segmented or non-segmented. [1] [3] [4] All −ssRNA genomes contain terminal inverted repeats, which are palindromic nucleotide sequences at each end of the genome. [5]

  9. Polyadenylation - Wikipedia

    en.wikipedia.org/wiki/Polyadenylation

    By convention, RNA sequences are written in a 5′ to 3′ direction. The 5′ end is the part of the RNA molecule that is transcribed first, and the 3end is transcribed last. The 3end is also where the poly(A) tail is found on polyadenylated RNAs. [1] [9]