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  2. Glucose-6-phosphate dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/Glucose-6-phosphate_de...

    G6PD converts G6P into 6-phosphoglucono-δ-lactone and is the rate-limiting enzyme of the pentose phosphate pathway. Thus, regulation of G6PD has downstream consequences for the activity of the rest of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase is stimulated by its substrate G6P.

  3. Glucose-6-phosphate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/Glucose-6-phosphate_de...

    The Beutler fluorescent spot test is a rapid and inexpensive test that visually identifies NADPH produced by G6PD under ultraviolet light. When the blood spot does not fluoresce, the test is positive; it can be falsely negative in patients who are actively hemolysing. It can therefore only be done 2–3 weeks after a hemolytic episode. [23]

  4. 6-phosphogluconate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/6-phosphogluconate_de...

    People suffering from 6PGD or G6PD deficiency (or both) are at risk of hemolytic anemia in states of oxidative stress. Oxidative stress can result from infection and from chemical exposure to medication and certain foods. Broad beans, e.g., fava beans, contain high levels of vicine, divicine, convicine and isouramil, all of which are oxidants.

  5. Beutler test - Wikipedia

    en.wikipedia.org/wiki/Beutler_test

    The Beutler test, also known as the fluorescent spot test, [1] is a screening test used to identify enzyme defects. [2] [3] [4] ... "G6PD deficiency". Blood. 84 (11): ...

  6. Glucose 6-phosphate - Wikipedia

    en.wikipedia.org/wiki/Glucose_6-phosphate

    This is a very efficient storage mechanism for glucose since it costs the body only 1 ATP to store the 1 glucose molecule and virtually no energy to remove it from storage. It is important to note that glucose 6-phosphate is an allosteric activator of glycogen synthase, which makes sense because when the level of glucose is high the body should ...

  7. Glucose 6-phosphatase - Wikipedia

    en.wikipedia.org/wiki/Glucose_6-phosphatase

    Corresponding residues in the active site of glucose 6-phosphatase-α include Arg170 and Arg83, which donate hydrogen ions to the phosphate, stabilizing the transition state, His119, which provides a proton to the dephosphorylated oxygen attached to glucose, and His176, which completes a nucleophilic attack on the phosphate to form a covalently ...

  8. Lipid metabolism - Wikipedia

    en.wikipedia.org/wiki/Lipid_metabolism

    [2] [3] The majority of lipids found in the human body from ingesting food are triglycerides and cholesterol. [4] Other types of lipids found in the body are fatty acids and membrane lipids . Lipid metabolism is often considered the digestion and absorption process of dietary fat; however, there are two sources of fats that organisms can use to ...

  9. Vicine - Wikipedia

    en.wikipedia.org/wiki/Vicine

    Vicine is an inactive compound in the body. When vicine enters the body through food, it is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine. [2] Upon hydrolysis, the glucose part of the molecule is split off and that results in the reduced divicine.

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