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Generic sildenafil (and brand-name Viagra) is a medication for the treatment of ED, Raynaud’s phenomenon, and pulmonary arterial hypertension. To understand how Viagra works, we need to look at ...
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]
To understand how long an ED medication will last, you need to know its half-life — which measures how long it takes for the concentration of the medication in your body to fall to half of its peak.
However, in rare cases, sildenafil treatment could also cause more severe or bothersome side effects. Sildenafil side effects are generally mild and fade over time, but they occur more frequently ...
Both partners' sexual experience also affects latency time. [5] A 2008 survey of Canadian and American sex therapists stated that the average time for heterosexual intercourse (coitus) was 7 minutes and that 1 to 2 minutes was too short, 3 to 7 minutes was adequate and 7 to 13 minutes desirable, while 13 to 30 minutes was too long. [6] [7]
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
For example, a small study of 20 people that looked into Viagra’s effect on refractory time found that a standard 100mg dose of sildenafil citrate reduced the average male post-intimacy recovery ...
The current most common treatment for ED, the oral PDE5 inhibitor known as sildenafil (Viagra) was approved for use for Pfizer by the FDA in 1998, which at the time of release was the fastest selling drug in history.
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