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Dilation and constriction of the pupil. Pupillary response is a physiological response that varies the size of the pupil, via the optic and oculomotor cranial nerve.. A constriction response (), [1] is the narrowing of the pupil, which may be caused by scleral buckles or drugs such as opiates/opioids or anti-hypertension medications.
The terms 'opioid' and 'opiate' are sometimes used interchangeably, but the term 'opioid' is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain. [4] Opiates are alkaloid compounds naturally found in the opium poppy plant Papaver somniferum. [5] [6]
Opiate overdose symptoms and signs can be referred to as the "opioid toxidrome triad": decreased level of consciousness, pinpoint pupils and respiratory depression. Other symptoms include seizures and muscle spasms. Sometimes an opiate overdose can lead to such a decreased level of consciousness such that the person will not wake up.
The pupil diameter can vary greatly due to various factors (primarily the pupillary light reflex), from constriction to as small as 2 mm, to dilation larger than 8 mm in some individuals, though the maximal dilation also varies substantially by individual and decreases with age. The pupil gets wider in the dark and narrower in light.
It’s easier than ever for doctors to prescribe a key medicine for opioid addiction since the U.S. government lifted an obstacle last year. But despite the looser restrictions and the ongoing ...
Pethidine is the most widely used opioid in labour and delivery. [16] It has fallen out of favour in some countries, such as the United States, in favour of other opioids, due to its potential drug interactions, especially with serotonergics, and its neurotoxic metabolite, norpethidine. [10]
Her bright blue eyes and bright-blonde curls make her a more unique French porcelain doll too. 6. 19th Century J. Bourgoin Talking Porcelain Doll. art-collector-cat/ebay. Price on eBay: $7,750.
The company experienced a system issue that affected multiple products including account withdrawals, peer-to-peer payment service Venmo, online checkout and crypto. PayPal said the issue, which ...