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Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. [1] FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland [ 2 ] and regulates the development, growth, pubertal maturation , and reproductive processes of the body.
Gonadotropic cells (also known as gonadotropes, gonadotrophs, delta cells, or delta basophils) are endocrine cells in the anterior pituitary that produce gonadotropins.More specifically, gonadotrophs produce and secrete glycoprotein polypeptide hormones, such as the follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are released due to the positive input of gonadotropin ...
Failure or loss of the gonads usually results in elevated levels of LH and FSH in the blood. [10] [11] LH insensitivity, which results in Leydig cell hypoplasia in males, and FSH insensitivity, are conditions of insensitivity to LH and FSH, respectively, caused by loss-of-function mutations in their respective
An earlier name for the same protein was FSH-suppressing protein (FSP). At the time of its initial isolation from follicular fluid , it was found to inhibit the anterior pituitary 's secretion of follicle-stimulating hormone (FSH).
The anterior pituitary complex and hypophyseal portal system, where FSH and LH are released. Theca cells are responsible for synthesizing androgens, providing signal transduction between granulosa cells and oocytes during development by the establishment of a vascular system, providing nutrients, and providing structure and support to the follicle as it matures.
Dogs with a bacterial infection feel an increased need to urinate. Some dogs will have dark urine or other signs of illness and, when treated with antibiotics and other treatments, this can clear ...
Identified in 1986, [1] [2] activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, [3] metabolism, homeostasis, immune response, wound repair, [4] and endocrine ...
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