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Affected areas become progressively more alopecic. The pattern of hairlessness that results is somewhat breed-dependent and sex dependent. In short-coated toy and miniature dogs, ventral neck, ventral chest, ventral abdomen and inner thighs are affected. In males, the pinnae (ear flaps) are affected.
Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. [1] FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland [ 2 ] and regulates the development, growth, pubertal maturation , and reproductive processes of the body.
Hypergonadotropic hypogonadism (HH), also known as primary or peripheral/gonadal hypogonadism or primary gonadal failure, is a condition which is characterized by hypogonadism which is due to an impaired response of the gonads to the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and in turn a lack of sex steroid production. [1]
Sertoli cells are required for male sexual development. Sertoli cell proliferation and differentiation is mainly activated by FGF9, with which they also form a feedforward loop. [4] [5] It has been suggested that Sertoli cells may derive from the fetal mesonephros. [6] After puberty, Sertoli cells begin to elongate.
The symptoms may be subtle and are often initially attributed to other causes. [1] [6] In most of the cases, three or more hormones are deficient. [7] The most common problem is insufficiency of follicle-stimulating hormone (FSH) and/or luteinizing hormone (LH) leading to sex hormone abnormalities.
The post Inflammatory Skin Disease in Dogs: Symptoms, Causes, & Treatments appeared first on DogTime. Inflammatory skin disease in dogs is a condition that involves a dog's skin glands. Usually ...
FSH acts on Sertoli cells in the male and follicular cells in the female. Combined this causes the secretion of gonadal sex steroids and the initiation of folliculogenesis and spermatogenesis . The production of sex steroids forms a negative feedback loop acting on both the anterior pituitary and hypothalamus causing a pulsatile secretion of ...
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