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With a normal P a O 2 of 60–100 mmHg and an oxygen content of F I O 2 of 0.21 of room air, a normal P a O 2 /F I O 2 ratio ranges between 300 and 500 mmHg. A P a O 2 /F I O 2 ratio less than or equal to 200 mmHg is necessary for the diagnosis of acute respiratory distress syndrome by the AECC criteria. [7]
The oxygenation index is a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body. A lower oxygenation index is better - this can be inferred by the equation itself. As the oxygenation of a person improves, they will be able to achieve a higher PaO2 at a lower FiO2.
This is calculated by dividing the PaO2 by the FiO2. Example: patient who is receiving an FiO2 of .5 (i.e., 50%) with a measured PaO2 of 60 mmHg has a PaO 2 / FiO 2 ratio of 120. In healthy lungs, the Horowitz index depends on age and usually falls between 350 and 450.
The normal range of P a O 2:F i O 2 ratio is 300 to 500 mmHg, if this ratio is lower than 300 it may indicate a deficit in gas exchange, which is particularly relevant for identifying acute respiratory distress syndrome (ARDS). A ratio of less than 200 indicates severe hypoxemia. [8]
Partial pressures of inhaled oxygen exceeding 0.6 bar (FIO2 >0.6 at normal atmospheric pressure), ... Normally, PaO2 ranges from 75 to 100 mmHg, ...
The simple face mask can deliver higher flow rates than nasal cannula (6–10 liters per minute) for an FiO2 of 30- 60% oxygen. [1] Nasal cannula and simple face masks are described as low flow delivery systems. [2] [3] Unlike the non-rebreather and partial rebreather masks, the simple face mask lacks a reservoir bag.
The alveolar oxygen partial pressure is lower than the atmospheric O 2 partial pressure for two reasons.. Firstly, as the air enters the lungs, it is humidified by the upper airway and thus the partial pressure of water vapour (47 mmHg) reduces the oxygen partial pressure to about 150 mmHg.
Arterial blood oxygen tension (normal) P a O 2 – Partial pressure of oxygen at sea level (160 mmHg (21.3 kPa) in the atmosphere, 21% of the standard atmospheric pressure of 760 mmHg (101 kPa)) in arterial blood is between 75 and 100 mmHg (10.0 and 13.3 kPa).