Search results
Results from the WOW.Com Content Network
Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside . [1] [2] The term can also refer more generally to any organic molecule that contains amino sugar substructures.
Netilmicin (1-N-ethylsisomicin) is a semisynthetic aminoglycoside antibiotic, and a derivative of sisomicin, produced by Micromonospora inyoensis. Aminoglycoside antibiotics have the ability to kill a wide variety of bacteria. Netilmicin is not absorbed from the gut and is therefore only given by injection or infusion.
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Download as PDF; Printable version; ... Pages in category "Aminoglycoside antibiotics" ... This page was last edited on 12 August 2023, ...
[32] [30] The gentamicin complex, is differentiated into five major components (C 1, C 1a, C 2, C 2a, C 2b) and multiple minor components by substitution at the 6' carbon of the purpurosamine unit indicated in the image to the right by R 1 and R 2. [32] [30] [33] [34] The R 1 and R 2 can have the follow substitutions for some of the species in ...
Streptothricins are a group of antibiotics in the aminoglycoside class. [1] The first antibiotic in the group was isolated from Streptomyces lavendulae in 1942. [ 2 ] It was later determined to be a mixture of closely-related compounds, and is now known as nourseothricin .
The aminopenicillins are a group of antibiotics in the penicillin family that are structural analogs of ampicillin (which is the 2-amino derivative of benzylpenicillin, hence the name). [1] Like other penicillins and beta-lactam antibiotics, they contain a beta-lactam ring that is crucial to its antibacterial activity. [citation needed]
Neomycin is an aminoglycoside antibiotic that displays bactericidal activity against Gram-negative aerobic bacilli and some anaerobic bacilli where resistance has not yet arisen. It is generally not effective against Gram-positive bacilli and anaerobic Gram-negative bacilli. Neomycin comes in oral and topical formulations, including creams ...