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  2. Cerebroretinal microangiopathy with calcifications and cysts

    en.wikipedia.org/wiki/Cerebroretinal...

    Neurologic symptoms and signs vary depending on the site of the brain abnormalities. Common symptoms are partial epilepsy, asymmetric spasticity, ataxia and cognitive impairment. [1] [2] [3] The latter affects visuospatial and visuoconstructive skills first. The intracranial pressure can be elevated if cysts develop in the brain.

  3. Neurodegenerative disease - Wikipedia

    en.wikipedia.org/wiki/Neurodegenerative_disease

    [70] [68] Increased oxidative DNA damage in the brain is associated with Alzheimer's disease and Parkinson's disease. [70] Defective DNA repair has been linked to neurodegenerative disorders such as Alzheimer's disease, amyotrophic lateral sclerosis, ataxia telangiectasia, Cockayne syndrome, Parkinson's disease and xeroderma pigmentosum. [70] [69]

  4. Central nervous system fatigue - Wikipedia

    en.wikipedia.org/wiki/Central_Nervous_System_Fatigue

    In the brain, serotonin is a neurotransmitter and regulates arousal, behavior, sleep, and mood, among other things. [9] During prolonged exercise where central nervous system fatigue is present, serotonin levels in the brain are higher than normal physiological conditions; these higher levels can increase perceptions of effort and peripheral muscle fatigue. [9]

  5. Aging brain - Wikipedia

    en.wikipedia.org/wiki/Aging_brain

    [6] [7] Regional volume reduction is not uniform; some brain regions shrink at a rate of up to 1% per year, whereas others remain relatively stable until the end of the life-span. [8] The brain is very complex, and is composed of many different areas and types of tissue, or matter.

  6. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's_disease

    The normal life expectancy for 60 to 70 years old is 23 to 15 years; for 90 years old it is 4.5 years. [228] Following AD diagnosis it ranges from 7 to 10 years for those in their 60s and early 70s (a loss of 13 to 8 years), to only about 3 years or less (a loss of 1.5 years) for those in their 90s.

  7. Map shows the average life expectancy for people in each state

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  8. Myalgic encephalomyelitis/chronic fatigue syndrome - Wikipedia

    en.wikipedia.org/.../chronic_fatigue_syndrome

    [1]: 29–30 In the WHO's most recent classification, the ICD-11, chronic fatigue syndrome and myalgic encephalomyelitis are named under post-viral fatigue syndrome. [27] The term post-infectious fatigue syndrome was initially proposed as a subset of "chronic fatigue syndrome" with a documented triggering infection, but might also be used as a ...

  9. Gerstmann–Sträussler–Scheinker syndrome - Wikipedia

    en.wikipedia.org/wiki/Gerstmann–Sträussler...

    Universally fatal, life expectancy is typically 5-6 years from diagnosis Gerstmann–Sträussler–Scheinker syndrome ( GSS ) is an extremely rare, always fatal (due to it being caused by prions ) neurodegenerative disease that affects patients from 20 to 60 years in age.