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Since dogs are insulin dependent, oral diabetes drugs, which require a functional endocrine pancreas with beta cells capable of producing insulin, are ineffective. [11] [50] [51] [10] Diabetic dogs require insulin therapy, [52] which must be continued for life. [11] [53]
The symptoms of an episode of diabetic ketoacidosis usually evolve over a period of about 24 hours. Predominant symptoms are nausea and vomiting, pronounced thirst, excessive urine production and abdominal pain that may be severe. [13] [14] In severe DKA, breathing becomes rapid and of a deep, gasping character, called "Kussmaul breathing".
While ketosis refers to any elevation of blood ketones, ketoacidosis is a specific pathologic condition that results in changes in blood pH and requires medical attention. The most common cause of ketoacidosis is diabetic ketoacidosis but it can also be caused by alcohol, medications, toxins, and rarely, starvation. [citation needed]
Ketoacidosis is most commonly caused by a deficiency of insulin in type 1 diabetes or late stage type 2 diabetes but can also be the result of chronic heavy alcohol use, salicylate poisoning, or isopropyl alcohol ingestion. [1] [2] Ketoacidosis causes significant metabolic derangements and is a life-threatening medical emergency. [2]
Type 1 diabetes requires treatment with insulin, ideally using a "basal bolus" regimen that most closely matches normal insulin release: long-acting insulin for the basal rate and short-acting insulin with meals. [131] Type 2 diabetes is generally treated with medication that is taken by mouth (e.g. metformin) although some eventually require ...
Disadvantages of mitotane as a treatment include the side effects and the requirement for blood test monitoring. Issues can arise when too much of the adrenal cortex becomes eroded. Approximately 30% of dogs will experience a reaction in response to treatment with mitotane; prednisone may be used as an antidote. In the event of a reaction ...
Symptoms of the unknown illness start like known canine infections such as kennel cough and strep zoo. ... Even if your dog vomits after consuming the drug, you have to make sure you wear gloves ...
[1] [2] Other conditions that can produce similar symptoms include infections, exposure to other toxic alcohols, serotonin syndrome, and diabetic ketoacidosis. [2] Early treatment increases the chance of a good outcome. Treatment consists of stabilizing the person and using an antidote.
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