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Simplified control circuit of human thermoregulation. [8]The core temperature of a human is regulated and stabilized primarily by the hypothalamus, a region of the brain linking the endocrine system to the nervous system, [9] and more specifically by the anterior hypothalamic nucleus and the adjacent preoptic area regions of the hypothalamus.
The human body always works to remain in homeostasis. One form of homeostasis is thermoregulation. Body temperature varies in every individual, but the average internal temperature is 37.0 °C (98.6 °F). [1] Sufficient stress from extreme external temperature may cause injury or death if it exceeds the ability of the body to thermoregulate.
Chloride is an anion in the human body needed for metabolism (the process of turning food into energy). [1] It also helps keep the body's acid-base balance. The amount of serum chloride is carefully controlled by the kidneys. [2] Chloride ions have important physiological roles.
Chloride is present in all body fluids, [12] and is the most abundant extracellular anion which accounts for around one third of extracellular fluid's tonicity. [ 13 ] [ 14 ] Chloride is an essential electrolyte , playing a key role in maintaining cell homeostasis and transmitting action potentials in neurons. [ 15 ]
This is one of the effectors in the homeostatic control of body temperature, and therefore highly variable in rough proportion to the heat load that threatens to destabilize the body's core temperature, for which there is a sensor in the hypothalamus of the brain. [citation needed]
A 2022 Outside article on heat stroke cites the highest known body temperature that a human was able to survive: “The highest body temperature measured was only 17 degrees above normal. Willie ...
Other factors which affect decompression risk include oxygen concentration, carbon dioxide levels, body position, environmental temperature and its effects on body temperature and temperature distribution, vasodilators and constrictors, positive or negative pressure breathing.
Other circumstances also affect the body's temperature. The core body temperature of an individual tends to have the lowest value in the second half of the sleep cycle; the lowest point, called the nadir, is one of the primary markers for circadian rhythms. The body temperature also changes when a person is hungry, sleepy, sick, or cold.