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A lung nodule or pulmonary nodule is a relatively small focal density in the lung. A solitary pulmonary nodule (SPN) or coin lesion, [1] is a mass in the lung smaller than three centimeters in diameter. A pulmonary micronodule has a diameter of less than three millimetres. [2] There may also be multiple nodules.
The calcified nodule can be within the lung, hila, or mediastinum. The borders must be sharp, distinct, and well defined. This was considered a Class B3 TB in the past; however, Class B3 has been omitted from the classification scheme because it has not been found to be associated with active TB.
Pulmonary tuberculomas are among the most common benign nodules, with 5%-24% of all resected nodules being of tuberculous origin. [21] In areas of lower prevalence, such as the United States, they are most commonly seen in the setting of an acquired immunodeficiency . [ 23 ]
Many authors argue that this pattern precludes the need for a lung biopsy in most cases. [ 5 ] [ 18 ] [ 19 ] After PAM is diagnosed in a given patient, family members should be screened by chest radiography, and parents should be counseled that future children are also at risk of developing the disease.
A lung nodule is a discrete opacity in the lung which may be caused by: Neoplasm: benign or malignant; Granuloma: tuberculosis; Infection: round pneumonia; Vascular: infarct, varix, granulomatosis with polyangiitis, rheumatoid arthritis; There are a number of features that are helpful in suggesting the diagnosis: rate of growth
High-resolution CT image showing ground-glass opacities in the periphery of both lungs in a patient with COVID-19 (red arrows). The adjacent normal lung tissue with lower attenuation appears as darker areas. Ground-glass opacity (GGO) is a finding seen on chest x-ray (radiograph) or computed tomography (CT) imaging of the lungs.
For lung nodules, air bronchograms used to be associated with infectious causes of consolidation and, therefore to be benign. However, in the setting of a lung nodule, an air bronchogram is actually more frequent in malignant than in benign nodules. [1] [4] studied the tumour-bronchus relationship and described five types: [1]
Severe infections can cause hepatosplenomegaly, lymphadenopathy, and adrenal enlargement. [4] Lesions often left calcification nodules as they are healed. [12] Presumed ocular histoplasmosis syndrome causes chorioretinitis, where the choroid and retina of the eyes are scarred, resulting in a loss of vision not unlike macular degeneration.
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