Search results
Results from the WOW.Com Content Network
An accessory spleen is a small nodule of splenic tissue found apart from the main body of the spleen. Accessory spleens are found in approximately 10 percent of the population [1] and are typically around 1 centimetre in diameter. They may resemble a lymph node or a small spleen.
The spleen, in healthy adult humans, is approximately 7 to 14 centimetres (3 to 5 + 1 ⁄ 2 in) in length. An easy way to remember the anatomy of the spleen is the 1×3×5×7×9×10×11 rule. The spleen is 1 by 3 by 5 inches (3 by 8 by 13 cm), weighs approximately 7 oz (200 g), and lies between the ninth and eleventh ribs on the left-hand side ...
Gandy–Gamna nodules may also be seen in chronic pulmonary congestion. Gandy–Gamna nodules or Gandy-Gamna bodies, sometimes known as Gamna-Gandy bodies or Gamna-Gandy nodules, are small yellow-brown, brown, or rust-colored foci found in the spleen in patients with splenomegaly due to portal hypertension, [1] as well as sickle cell disease.
In the human until the fifth month of prenatal development, the spleen creates red blood cells; after birth, the bone marrow is solely responsible for hematopoiesis. As a major lymphoid organ and a central player in the reticuloendothelial system, the spleen retains the ability to produce lymphocytes. The spleen stores red blood cells and ...
In humans the splenic marginal zone B cells have evidence of somatic hypermutation in their immunoglobulin genes, indicating that they have been generated through a germinal centre reaction to become memory cells. While naive MZ B cells produce low-affinity IgM antibodies, memory MZ B cells express high-affinity Ig molecules.
White pulp is a histological designation for regions of the spleen (named because it appears whiter than the surrounding red pulp on cross section), that encompasses approximately 25% of splenic tissue. White pulp consists entirely of lymphoid tissue.
Macroscopically, splenosis manifests as individual pieces of reddish-blue tissue with variable shape, which can be as few as one and as many as 300, [4] mostly in the abdominal cavity, and varying in size from a few millimeters to as large as 12 cm. Due to the limited blood supply to these nodules, the typical size of splenic implants is ...
White pulp, splenic lymphoid nodules, or white nodules — follicles in the white pulp of the spleen, containing many lymphocytes These structures are named after Marcello Malpighi (1628–1694), an Italian physician and biologist regarded as the father of microscopical anatomy and histology .