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Cefoperazone contains an N-methylthiotetrazole (NMTT or 1-MTT) side chain.As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse effect), due to inhibition of aldehyde dehydrogenase.
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Cefoperazone/sulbactam is a combination drug used as an antibiotic. It is effective for the treatment of urinary tract infections . [ 2 ] It contains cefoperazone , a β-lactam antibiotic , and sulbactam , a β-lactamase inhibitor , which helps prevent bacteria from breaking down cefoperazone.
The fire – impacting both Los Angeles and Ventura counties – had burned more than 10,000 acres and is 14% contained as of Thursday morning, according to the California Department of Forestry ...
Greater Los Angeles is the most populous metropolitan area in the U.S. state of California, encompassing five counties in Southern California extending from Ventura County in the west to San Bernardino County and Riverside County in the east, with the city of Los Angeles and Los Angeles County at its center, and Orange County to the southeast.
The combination cefoperazone/sulbactam (Sulperazon) is available in many countries but not in the United States. [ 4 ] The co-packaged combination sulbactam/durlobactam was approved for medical use in the United States in May 2023.
The Food and Drug Administration has made updates to a December recall of over 2.4 million cases of MadeGood granola bars, warning consumers of adverse health risks associated with the recall. ...