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The Kurtzke Expanded Disability Status Scale (EDSS) is a method of quantifying disability in multiple sclerosis. [ 1 ] [ 2 ] The scale has been developed by John F. Kurtzke . [ 1 ] The EDSS is based on a neurological examination by a clinician.
In particular, Dr Kurtzke is widely known for his Expanded Disability Status Scale or EDSS (a method of quantifying disability in multiple sclerosis) [2] and for his pioneering work in the field of neuroepidemiology, a branch of epidemiology he helped to establish in 1967 with Dr. Len Kurland and Dr. Milton Alter. [3]
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The assessor requires little training for accurate completion and approximately fifteen minutes to score. The patient can perform the assessment retrospectively or it can be done using medical history. Secondly, the scale allows effective tracking of progress. [4] The scale is strongest and most sensitive in scaling general behavioral disability.
The modified UPDRS retains the four-scale structure with a reorganization of the various subscales. Score ranges from 0 to 260, [7] [8] with 0 indicating no disability and 260 indicating total disability. The scales are: Part I: Nonmotor experiences of daily living: 13 items. Score range: 0–52, [8] 10 and below is mild, 22 and above is severe ...
A score of 0 on a question would indicate no function while a score of 4 would indicate full function. [4] [5] This scale has been useful for doctors in diagnosing patients, measuring disease progression and also for researchers when selecting patients for a study and measuring the potential effects of a clinical trial. [4] [6]
The modified Rankin Scale (mRS) is a commonly used scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability. It has become the most widely used clinical outcome measure for stroke clinical trials. [1] [2]
Each question is scored on a scale of 0–5 with the first statement being zero and indicating the least amount of disability and the last statement is scored 5 indicating most severe disability. [2] The scores for all questions answered are summed, then multiplied by two to obtain the index (range 0 to 100).