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The Kurtzke Expanded Disability Status Scale (EDSS) is a method of quantifying disability in multiple sclerosis. [ 1 ] [ 2 ] The scale has been developed by John F. Kurtzke . [ 1 ] The EDSS is based on a neurological examination by a clinician.
John Francis Kurtzke (September 14, 1926 – December 1, 2015) was a neuroepidemiologist and Professor of Neurology at Georgetown University who is best known for his creation of the Expanded Disability Status Scale and for his research on multiple sclerosis (MS). [1]
The modified UPDRS retains the four-scale structure with a reorganization of the various subscales. Score ranges from 0 to 260, [7] [8] with 0 indicating no disability and 260 indicating total disability. The scales are: Part I: Nonmotor experiences of daily living: 13 items. Score range: 0–52, [8] 10 and below is mild, 22 and above is severe ...
The assessor requires little training for accurate completion and approximately fifteen minutes to score. The patient can perform the assessment retrospectively or it can be done using medical history. Secondly, the scale allows effective tracking of progress. [4] The scale is strongest and most sensitive in scaling general behavioral disability.
The modified Rankin Scale (mRS) is a commonly used scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability. It has become the most widely used clinical outcome measure for stroke clinical trials. [1] [2]
A score of 0 on a question would indicate no function while a score of 4 would indicate full function. [4] [5] This scale has been useful for doctors in diagnosing patients, measuring disease progression and also for researchers when selecting patients for a study and measuring the potential effects of a clinical trial. [4] [6]
Each question is scored on a scale of 0–5 with the first statement being zero and indicating the least amount of disability and the last statement is scored 5 indicating most severe disability. [2] The scores for all questions answered are summed, then multiplied by two to obtain the index (range 0 to 100).
In one study, higher average severity scores were associated with patients involved in litigation at the time the questionnaire was administered. [9] Studies using other neuropsychological assessments for post-concussion syndrome or general cognitive performance have also shown poor test-taker effort to affect the reported severity of symptoms ...