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Phenoxymethylpenicillin, also known as penicillin V (PcV) and penicillin VK, is an antibiotic useful for the treatment of a number of bacterial infections. [2] Specifically it is used for the treatment of strep throat , otitis media , and cellulitis . [ 2 ]
Penicillin is actively excreted, and about 80% of a penicillin dose is cleared from the body within three to four hours of administration. Indeed, during the early penicillin era, the drug was so scarce and so highly valued that it became common to collect the urine from patients being treated, so that the penicillin in the urine could be ...
Tonsillitis occurs throughout the world, without racial or ethnic differences. [48] Most children have tonsillitis at least once during their childhood, [49] although it rarely occurs before the age of two. [48] It most typically occurs between the ages of four and five; bacterial infections most typically occur at a later age. [48]
Strep throat is a common bacterial infection in children. [2] It is the cause of 15–40% of sore throats among children [7] [13] and 5–15% among adults. [8] Cases are more common in late winter and early spring. [13] Potential complications include rheumatic fever and peritonsillar abscess. [1] [2]
The antibiotics penicillin V and erythromycin are not effective for treating acute laryngitis. [16] Erythromycin may improve voice disturbances after a week and cough after 2 weeks, but any modest subjective benefit is not greater than the adverse effects, cost, and the risk of bacteria developing resistance to the antibiotics . [ 16 ]
The dosage may be increased up to 6 mg/kg/dose as needed, but not exceed the maximum dose for adults. For children with diseases other than above: 3 mg/kg/dose, 3 times a day after meals. The dosage may be adjusted according to the disease or the patients age and symptoms, but not exceed the maximum dose for adults.
The recommended dosage for oral penicillin is 5 to 10 mg per pound of body weight, once daily. The duration of the treatment typically ranges from seven to 14 days, but in some cases, longer ...
In 1986, some European countries banned the use of antibiotics because of research they found that linked antibiotic use in livestock and drug resistant bacteria in humans. [11] The European Union regulated in 2006 against antibiotics for growth promotion purposes. [12] It was estimated in 2014 that over 80% of the world's antibiotic use was on ...