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“Over time, this repeated damage can result in cirrhosis, where the liver becomes so scarred that it loses functionality,” she explains. This may eventually raise the risk of liver cancer. 2.
Long term excessive intake of alcohol can lead to damage to the central nervous system and the peripheral nervous system resulting in loss of sexual desire and impotence in men. [184] This is caused by reduction of testosterone from ethanol-induced testicular atrophy , resulting in increased feminisation of males and is a clinical feature of ...
Binge drinking, or heavy episodic drinking, can lead to damage in the limbic system that occurs after a relatively short period of time. This brain damage increases the risk of alcohol-related dementia, and abnormalities in mood and cognitive abilities. Binge drinkers also have an increased risk of developing chronic alcoholism.
Excessive alcohol intake (binge drinking) causes a decrease in hippocampal neurogenesis, via decreases in neural stem cell proliferation and newborn cell survival. [19] [20] Alcohol decreases the number of cells in S-phase of the cell cycle, and may arrest cells in the G1 phase, thus inhibiting their proliferation. [19]
The signs and symptoms of alcoholic cardiomyopathy (ACM) can vary depending on the severity of the condition. [6] In the early stages, people with ACM may not experience any symptoms. However, as the condition progresses, they may experience symptoms such as fatigue, shortness of breath, palpitations, and swelling of the legs and ankles. [ 6 ]
You don't have to drink alcohol every day to be classified as having a problem — binge drinking a few times a week can interfere with your life just as much as daily drinking, Nelson says.
A person consuming a dangerous amount of alcohol persistently can develop memory blackouts and idiosyncratic intoxication or pathological drunkenness symptoms. [36] Long-term persistent consumption of excessive amounts of alcohol can cause liver damage and have other deleterious health effects.
Because ethanol is mostly metabolized and consumed by the liver, chronic excessive use can lead to fatty liver. This leads to a chronic inflammation of the liver and eventually alcoholic liver disease. Alcohol consumption can cause hypoglycemia in diabetics on certain medications, such as insulin or sulfonylurea, by blocking gluconeogenesis. [65]