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Pseudobulbar affect (PBA), or emotional incontinence, is a type of neurological disorder characterized by uncontrollable episodes of crying or laughing. PBA occurs secondary to a neurologic disorder or brain injury. Patients may find themselves crying uncontrollably at something that is only slightly sad, being unable to stop themselves for ...
Since pseudobulbar palsy is a syndrome associated with other diseases, treating the underlying disease may eventually reduce the symptoms of pseudobulbar palsy. [ citation needed ] Possible pharmacological interventions for pseudobulbar affect include the tricyclic antidepressants , serotonin reuptake inhibitors , and a novel approach utilizing ...
Avanir Pharmaceuticals (NAS: AVNR) is a biotechnology company developing therapies focused on the central nervous system. It has one drug currently approved by the Food and Drug Administration ...
It can show a low compound muscle action potential (CMAP), which results from the loss of motor neurons, but the sensory neurons should remain unaffected. [20] Tissue biopsy: Taking a small sample of a muscle or nerve may be necessary if the EMG/NCS is not specific enough to rule out other causes of progressive muscle weakness, but it is rarely ...
Emotional lability is seen or reported in various conditions including borderline personality disorder, [3] histrionic personality disorder, [4] post-traumatic stress disorder, [5] hypomanic or manic episodes of bipolar disorder, [6] and neurological disorders or brain injury (where it is termed pseudobulbar affect), such as after a stroke. [7]
The cause of PBP is unknown. One form of PBP is found to occur within patients that have a CuZn-superoxide dismutase (SOD1) mutation. [7] Progressive bulbar palsy patients that have this mutation are classified with FALS patients, Familial ALS (FALS) accounts for about 5%-10% of all ALS cases and is caused by genetic factors.
A male with gluten ataxia: previous situation and evolution after 3 months of gluten-free diet.. There are many causes of cerebellar ataxia including, among others, gluten ataxia, [7] autoimmunity to Purkinje cells or other neural cells in the cerebellum, [8] CNS vasculitis, multiple sclerosis, infection, bleeding, infarction, tumors, direct injury, toxins (e.g., alcohol), genetic disorders ...
The tests differ in the rotation of the arm; in the empty can test, the arm is rotated to full internal rotation (thumb down) and in the full can test, the arm is rotated to 45° external rotation, thumb up. [1] Once rotated, the clinician pushes down on either the wrists or the elbow, and the patient is instructed to resist the downward pressure.
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