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Insensible perspiration, also known as transepidermal water loss, is the passive vapour diffusion of water through the epidermis. Insensible perspiration takes place at an almost constant rate and reflects evaporative loss from the epithelial cells of the skin. [1] Unlike sweating, the lost fluid is pure without additional solutes. For this ...
These are termed "insensible fluid losses" as they cannot be easily measured. Some sources say insensible losses account for 500 to 650 ml/day (0.5 to 0.6 qt.) of water in adults, [12] [14] while other sources put the minimum value at 800 ml (0.8 qt.). [15] In children, one calculation used for insensible fluid loss is 400 ml/m 2 body surface area.
Excess free water or hypotonic water can leave the body in two ways – sensible loss such as osmotic diuresis, sweating, vomiting and diarrhea, and insensible water loss, occurring mainly through the skin and respiratory tract. In humans, dehydration can be caused by a wide range of diseases and states that impair water homeostasis in the body ...
Web corpus searches show that the acronym TEWL is about 40 times more common than TWL in reference to transepidermal water loss. A large advantage of TEWL is that it has higher specificity to that sense than does TWL, which has more alternative senses, including, most importantly, two other senses having to do with evaporation of body water: thermal work limit (TWL), which is the highest ...
The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.
Oral: Differentiation syndrome, hyperleucocytosis, elevated cholesterol and triglycerides, arrhythmias, pancreatitis, elevated liver enzymes, thrombosis, intracranial hypertension and pseudotumour cerebri (mainly in children), anxiety, depression and genital ulceration (rare). Topical: Erythema. 2.4 Immunomodulatory Agents (IMiDs) Lenalidomide: PO
Intravascular administration does not involve absorption, and there is no loss of drug. [4] The fastest route of absorption is inhalation. [5] Absorption is a primary focus in drug development and medicinal chemistry, since a drug must be absorbed before any medicinal effects can take place. Moreover, the drug's pharmacokinetic profile can be ...
Many drugs have more than one name and, therefore, the same drug may be listed more than once. Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs , ranked by sales.