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The liver parenchyma is the functional tissue of the organ made up of around 80% of the liver volume as hepatocytes. The other main type of liver cells are non-parenchymal. Non-parenchymal cells constitute 40% of the total number of liver cells but only 6.5% of its volume. [11]
A perivascular space, also known as a Virchow–Robin space, is a fluid-filled space surrounding certain blood vessels in several organs, including the brain, [1] potentially having an immunological function, but more broadly a dispersive role for neural and blood-derived messengers. [2]
The total fluid volume of the interstitium during health is about 20% of body weight, but this space is dynamic and may change in volume and composition during immune responses and in conditions such as cancer, and specifically within the interstitium of tumors. [2] The amount of interstitial fluid varies from about 50% of the tissue weight in ...
In humans, the intracellular compartment contains on average about 28 liters (6.2 imp gal; 7.4 U.S. gal) of fluid, and under ordinary circumstances remains in osmotic equilibrium. It contains moderate quantities of magnesium and sulfate ions. In the cell nucleus, the fluid component of the nucleoplasm is called the nucleosol. [4]
The main component of the extracellular fluid (ECF) is the interstitial fluid, or tissue fluid, which surrounds the cells in the body. The other major component of the ECF is the intravascular fluid of the circulatory system called blood plasma. The remaining small percentage of ECF includes the transcellular fluid.
The total body of water is divided into fluid compartments, [1] between the intracellular fluid compartment (also called space, or volume) and the extracellular fluid (ECF) compartment (space, volume) in a two-to-one ratio: 28 (28–32) liters are inside cells and 14 (14–15) liters are outside cells.
The functional substance, or parenchyma, of the human kidney is divided into two major structures: the outer renal cortex and the inner renal medulla. Grossly, these structures take the shape of eight to 18 cone-shaped renal lobes, each containing renal cortex surrounding a portion of medulla called a renal pyramid. [18]
The pathway consists of a para-arterial influx mechanism for CSF driven primarily by arterial pulsation [2], which "massages" the low-pressure CSF into the denser brain parenchyma, and the CSF flow is regulated during sleep by changes in parenchyma resistance due to expansion and contraction of the extracellular space.